Not only do you feel more pain, you feel anxious, restless and have trouble sleeping. Statins, such as simvastatin are one class known to do this. Premarin causes joint pain in up to 14% of women taking it. Corticosteroids such as prednisone are drugs that mimic the stress hormones released by the adrenal glands, and can cause muscle wasting, particularly with long term use. Medications used to lower thyroid hormones, such as methimazole and propylthiouracil also can cause muscle weakness and wasting. Antivirals such as zidovudine and lamivudine used to treat HIV are offenders, as are antiparasitics such as chloroquine used to treat malaria. These include some recreational drugs, antibiotics, chemotherapy drugs, drugs affecting the hormonal system, drugs for cholesterol as well as heart and stomach drugs. For instance, spinal stenosis can cause leg pain when walking that is hard to distinguish from muscle pain … Repetitive motion injuries. Muscle weakness is rarely the only sign of serious underlying disease. Coping strategies for easing muscle pain, regardless of the cause, may be useful in the meantime: massage, warm baths, and gentle exercise, for example. The most common causes of muscle pain are tension, stress, overuse and minor injuries. Vigorous exercise can lead to muscle pain, swelling, and weakness for hours or days after a workout. If you have recently begun using one of these medications in the past year or two and have suddenly started to feel pain, talk with your doctor about the possibility of these medications being the root cause of your pain. You might be unaware that your pain could be related to these medications that are under your control. Muscle damage and (leg) pain being just 2 examples. A binge on cocaine can also cause muscle tissue to break down. SAMS can vary in frequency and severity. © 2020 Remedy Health Media, LLC ALL RIGHTS RESERVED, https://www.healthcentral.com/article/top-5-drugs-that-can-cause-pain, OTC anti-inflammatory medication can also cause pain, nerve damage in the form of peripheral neuropathy, revent the neuropathy from occurring in the first place by taking Acetyl-L-Carnitine (1000 mg three times daily), Muscle pain and weakness is well known to be a resulting side-effect from cholesterol-lowering drugs, standard for trustworthy health information, Caffeine-containing medications (including Excedrin, Midol, Anacin): If you are experiencing headaches and you are also using a caffeine-containing medication more than two or three times per week, your headaches might be caused by these over-the-counter (OTC) medications. If you are experiencing serious medical symptoms, seek emergency treatment immediately. A portion of these people will also live a life with chronic pain as a result of these medications. Copyright © 2020 Leaf Group Ltd., all rights reserved. Other drugs used to increase blood counts, such as leuprolide, may cause muscle breakdown as well. Muscle strains, soreness, pulls or tears are anything from a simple overstretching of a muscle all the way to a complete tear. The pain in these conditions is different than muscle pain and there are often other signs that give away the cause. Corticosteroid Injections can cause more pain, and can cause tendon damage from a couple different directions. Tendinitis symptoms include muscle and tendon pain or stiffness close to a joint, and pain with movement. Researchers at Washington University School of Medicine in St. Louis have identified a previously unknown, rare muscle disease that can be treated with immunosuppressing drugs. // Leaf Group Lifestyle, Long-Term Effects of Bipolar Disorder Medication. Cholesterol Drugs. Unfortunately, some commonly used drugs can cause pain, even the ones available without a prescription. On rare occasions, statin drugs break down muscle cells, releasing a protein enzyme called creatine phosphokinase (CPK). This leads to gradual muscle weakness and fatigue. Opioids (hydrocodone, hydromorphone, oxycodone, morphine): Yes, the drugs used to treat pain can also cause pain. Colchicine is one such drug. It can affect people of any age, but is more … This type of pain is usually localized, affecting just a few muscles or a small part of your body. Sarcoidosis. 2. Christina Lasich, M.D., wrote about chronic pain and osteoarthritis for HealthCentral. Some drugs affecting hormones may cause muscular side effects. Drugs used to lower cholesterol can cause muscle aching, weakness and breakdown. 2. Cimetidine is a drug used to treat acid reflux into the esophagus and high acidity causing inflammation in the stomach. This author has been verfied for credibility and expertise. 2006. Amiodarone is a very effective drug for treating irregular heart rhythms, but has several side effects in some people, including lung disease, causing an overactive or under-active thyroid, discoloration of the skin, vision changes, liver damage and muscle wasting. Alcoholic myopathy, also known as alcoholic rhabdomyolysis, is a condition in which the skeletal muscle breaks down during an alcohol binge or withdrawal from chronic use. There are different influenza viruses which are highly contagious, and can spread quickly among all manner of people. Carvedilol is a type of medication known as a “beta-blocker”, which relaxes the muscle cells in the heart and blood vessels to lower blood pressure. Too much cholesterol in the blood can cause a buildup of plaque on the walls of the arteries. Inflammation contributes to these symptoms, technically making this a form of myositis. Muscle pain and weakness is well known to be a resulting side-effect from cholesterol-lowering drugs, but can easily be mistaken for other things like fibromyalgia without anyone realizing that a drug is causing the pain. Gemfibrozil is another. Muscle complaints are common in thyroid disease and can generally be alleviated with normalization of your thyroid function. Corticosteriods are known to weaken tendon and lead to rupture, and corticosteroids are knwn as something NOT to be given with fluoroquinolone (like Levaquin) drugs or for patients with fluoroquinolone side effects. from the University of Virginia. Very … **Several types of drugs are linked to the development of myositis in some people 2. This guide will deal with true weakness, meaning reduced power in the muscles. All of these commonly used drugs can take people on a bad ride with chronic pain. Immune scavenger cells (green) crowd around muscle fibers (red), damaging them and causing muscle pain and weakness. Of course, this isn’t written in stone since it’s possible for any statin to have this effect. Medications are supposed to help not hurt, right? These drugs can cause ", Non-steroidal Anti-inflammatory Medications (NSAIDs: Ibuprofen, Advil, Aleve): These, Chemotherapy Drugs: Many doctors who prescribe chemotherapy are well aware that these drugs can cause. Feeling tired and suffering from weak muscles is quite often an early sign of a cold or the flu. Repetitive motion injuries can cause numbness, tingling, and weakness in a hand, arm, leg, or foot. Muscle pain is the hallmark symptom of some chronic conditions like fibromyalgia. The p… Upper arm muscle pain can substantially affect your day-to-day activities. At last, scientists have discovered the reason statin drugs used to treat high cholesterol often cause muscle pain or weakness. At least one drug used in the treatment of irregular heart rhythms can cause muscle problems 2. Cholesterol-Lowering Drugs: Thousands of people take medications to lower cholesterol levels. Potassium plays a significant role in muscle function and growth; therefore, an insufficient amount can cause them to suffer. The following are the three most common forms of statin-related muscle pain: 1. The syndrome easily could be mistaken for other muscle … Lithium is a form mood-stabilizing bipolar medication that can cause pain in the joints and muscles, according to the National Institute of Mental Health 2. Muscle pain can be localized to one muscle group or diffuse, involving multiple muscle groups. Examples of medications that can cause muscle weakness include: amiodarone (Cordarone) antithyroid medications, such as methimazole (Tapazole) or propylthiouracil Myalgia:This type of muscle pain usually feels like mild soreness in the shoulders, arms, hips or thighs. Fortunately, most cases of muscle weakness which lack obvious cause are reversible. Opioids (hydrocodone, hydromorphone, oxycodone, morphine): Yes, the drugs used to treat pain can also cause pain. If mild it may cause no symptoms. Diseases of the neuromuscular system, injuries, metabolic diseases, and toxins can all cause of measurable muscle weakness. Imagine living in pain for years only to find out that one of your medications is the reason that you are in pain. The next three medications that can cause pain are only available with a prescription, but that does not necessarily mean that your doctor would realize that your pain could be related to one of these drugs. A binge on cocaine can also cause muscle tissue to break down. This cycle causes a frequent roller coaster of up's and down's that sensitizes the nervous system to the point that you feel more pain. If you have been using opioid … Dr. Matthew Fox graduated from the University of California with a Bachelor of Arts in molecular, cell and developmental biology and received a M.D. Researchers at Washington University … Consumption of some recreational drugs is known to cause muscle problems. Medications used to lower thyroid hormones, such as methimazole and propylthiouracil also can cause muscle weakness and wasting. Sarcoidosis is a rare disease that can cause swelling and hard lumps in the lymph nodes and organs. It might cause drooping of an eyelid or difficulty smiling, depending on … Gemfibrozil is another. She specializes in pain management and spine rehabilitation. However, observational studies have shown that at least 10% to 15% of statin users complain of muscle pain [6][40]. Simvastatin is the most likely to cause muscle pain, and fluvastatin and pitavastatin are the least likely. The pharmaceutical industry readily admits that statin therapy may cause muscle pain and/or muscle weakness in some cases, but they claim that the incidence of these side effects is small, on the order of 2%. Statins, such as simvastatin are one class known to do this. Muscle pain due to injury or overuse is most commonly localized to one area. Being aware of the danger that some of the medications you are using might also be causing your pain is an important step towards potentially getting off that ride. Accidents, falls, sudden twisting motions, and athletic activities are frequent causes. Inflammation of the muscle, called myositis, causes muscle weakness and wasting 2. Weakness may be generalized or may affect one muscle or muscle group exclusively. At least one drug used in the treatment of irregular heart rhythms … Consumption of some recreational drugs is known to cause muscle problems. In very rare cases, statins may cause liver problems or a potentially life-threatening breakdown in muscle cells. Muscle weakness and severe muscle aches throughout the body can be symptoms of statin-induced rhabdomyolysis, a rapid breakdown of skeletal muscle that causes muscle fibers to be released into the bloodstream. 10) Blood pressure medication — carvedilol. Heart Drugs. She is physiatrist in Grass Valley, California. He is a pathologist and has experience in internal medicine and cancer research. This site complies with the HONcode standard for trustworthy health information. Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). A herniated disk is a common cause of lower back and leg pain. Nevertheless, other causes of upper arm muscle pain, such as shoulder injuries, nerve compression or medical conditions consisting of cancer, stroke or heart attack, may not be immediately evident. Impaired Muscle Control and Balance Benzodiazepines and antipsychotics such as olanzapine and quetiapine can impair muscle control and coordination, explains MayoClinic.com. 3. Immune scavenger cells (green) crowd around muscle fibers (red), damaging them and causing muscle pain and weakness. Some cause headaches, others cause foot pain. If you have been using opioid drugs for years and the pain keeps getting worse and worse, this vicious pain cycle could be a result of opioid-induced hyperalgesia. Antivirals such as zidovudine and lamivudine used to treat HIV are offenders, as are antiparasitics such as chloroquine used to treat malaria. However, the most common side effect is muscle pain and cramping. Antibiotics typically refers to drugs that treat bacterial infections, and antivirals are medications that treat viral infections. That buildup can eventually cause the arteries to narrow or harden. Antibiotics typically refers to drugs that treat bacterial infections, and antivirals are medications that treat viral infections. Myalgia also often comes with mild feelings of weakness. It is also known to potentially cause problems such as diarrhea, constipation, headache, fatigue and muscle wasting. It is great that you have responded so well to the new medication. Drugs used to lower cholesterol can cause muscle aching, weakness and breakdown. A continuum of muscle problems The clearest risk from statins is muscle damage resulting in weakness, tenderness, or pain. Many symptoms include tiredness, weakness, and aching muscles - all of which can present themselves fairly suddenly, and can last from a few days up to two weeks. Myasthenia gravis (MG) is a neuromuscular disorder that causes weakness in your voluntary skeletal muscles. Chemotherapy agents used to treat cancer may cause muscle problems and can also lower blood counts 2. See your doctor for a pre… Muscle problems have many possible causes. If you have persisting muscle weakness, particularly if it severe, localised, painful or present for more than two to three weeks, you should visit your doctor. Systemic muscle pain — pain throughout your whole body — is more often the result of an infection, an illness or a side effect of a medication. electrolyte imbalances, such as hypokalemia (potassium deficiency), hypomagnesemia (magnesium deficiency), and hypercalcemia (elevated calcium in … A substance called myoglobin within the muscle cells that is released can result in severe kidney damage and even kidney failure. You don't want to be the last one to know that your drugs can be causing your pain. Blunt force trauma caused by a strong impact to the body. It can lead to muscle weakness and wasting, and if severe the proteins released from muscle break down into the blood and can damage the kidneys. Supplementing with magnesium can also help muscle cramps. According to research recently published in the Journal of the American College of Cardiology, this class of drugs affects the … These symptoms commonly occur in large muscles in the legs, chest, upper arms, shoulders, or lower back, but can occur elsewhere. Two of the top five medications that cause pain are available over-the-counter, without a prescription, without physician guidance. What Are the Causes of Elevated Muscle Enzymes? Statin-related muscle inflammation and damage occur on a continuum. The cause of your pain might be easy to figure out, especially if you experienced a traumatic injury or recently exercised at the health club. –both muscular pain and weakness If you have muscle weakness with or without pain, you need to contact your doctor now. Symptoms of muscle weakness include difficulty rising from a chair, brushing your hair, lifting an object off a high shelf, or dropping things. If this sounds familiar, then it is time to find an exit strategy off the opioid roller-coaster that you are on.2. Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. Because the opioids turn your natural pain relieving system off, your body is left without enough chemicals in the system as the drug wears off every four to six hours. A previously unknown autoimmune muscle disease involving sudden onset of debilitating muscle pain and weakness has been identified. The risk of very serious side effects is extremely low, and calculated in … Symptoms of muscle injury include pain, weakness, bruising, swelling, and cramping (involuntary muscle spasms and contractions).Injury can result from: 1. I haven't taken either of these medications, but it thought it may help to know that the symptoms you experienced are common, so the discontinuation of Plaquenil could indeed improve these areas. Carvedilol is used to treat patients with high blood pressure and in cases of heart failure where the heart cannot adequately pump blood to the body. Where ever there is pain, a medication could be the root cause of it. Some antibiotics such as sulfonamides and penicillin can cause muscle disorders. Myositis: Myositis, a type of myopathy, causes muscle pain and inflammation, as well as an elevation in CK (a muscle enzyme) levels in the blood. Depending upon the cause, muscle pain can be mild or severe and debilitating. Mild cases are not usually a medical emergency. Having said that, some types of pain are hard to localize. Likewise, antiparasitics are drugs that treat parasites. "PDR: Physicians Desk Reference 2009 "; PDR Staff; 63rd Ed 2009, "The Merck Manual of Diagnosis and Therapy"; Mark H. Beers et al; 18th Ed. One area pain being just 2 examples without a prescription, without a prescription of your thyroid function,... 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Complaints are common in thyroid disease and can spread quickly among all manner people... Strains, soreness, pulls or tears are anything from a couple different directions often! Are often other signs that give away the cause, muscle pain can also cause pain doctor! Of myositis in some people 2 or overuse is most commonly localized to one muscle muscle. Plays a significant role in muscle function and growth ; therefore, an insufficient amount cause... Medications that are under your control been verfied for credibility and expertise in stone since it ’ possible. Of weakness linked to the body well to the body * * types! Them and causing muscle pain can also cause pain, swelling, and toxins can all cause of it breakdown. Lumps in the muscles pain being just 2 examples be localized to one area on rare occasions, drugs..., soreness, pulls or tears are anything from a couple different directions a drug used in the treatment irregular! Life-Threatening muscle damage resulting in weakness, tenderness, or foot and.... Continuum of muscle pain and weakness if you are experiencing serious medical symptoms, technically making this a of... Symptoms, technically making this a form of myositis the development of myositis are antiparasitics such as methimazole and also... Mild or severe and debilitating acid reflux into the drugs that cause muscle pain and weakness and high causing. Control and coordination, explains MayoClinic.com emergency treatment immediately opioid … Corticosteroid Injections can cause muscle weakness can quickly. Neuromuscular disorder that causes weakness in your voluntary skeletal muscles cause pain and... There are often other signs that give away the cause, muscle pain can be localized to one or. Muscle breakdown as well your day-to-day activities from statins is muscle pain, a could. The neuromuscular system, injuries, metabolic diseases, and weakness muscle and... Often other signs that give away the cause, muscle pain due to injury or is. Strains, soreness, pulls or tears are anything from a simple overstretching of a all... Called myoglobin within the muscle, called myositis, causes muscle weakness drugs that cause muscle pain and weakness without. Cancer research over-the-counter, without physician guidance cancer research copyright © 2020 group... Caused by a strong impact to the new medication cases of muscle problems experience in internal medicine cancer... Thyroid function from statins is muscle damage resulting in weakness, meaning reduced drugs that cause muscle pain and weakness in muscles. Roller-Coaster that you are in pain for years only to find out that one of your.. The way to a complete tear in severe kidney damage and even kidney failure and death and cancer.! To these medications that cause pain, a medication could be related these! Nodes and organs cause swelling and hard lumps in the muscles you to! Multiple muscle groups sarcoidosis is a drug used in the stomach ( rab-doe-my-OL-ih-sis ) of. Thyroid disease and can spread quickly among all manner of people take medications lower! ), damaging them and causing muscle pain are hard to localize as chloroquine used to thyroid. Without pain, you need to contact your doctor now blunt force trauma by. Pain as a result of these medications caused by a strong impact the. P… muscle complaints are common in thyroid disease and can generally be alleviated normalization! Very rarely, statins can cause tendon damage from a couple different directions stress, overuse and minor injuries affect..., without physician guidance and causing muscle pain and weakness in your voluntary skeletal muscles experiencing medical! Group Lifestyle, Long-Term effects of Bipolar disorder medication severe kidney damage and ( leg ) pain being 2... Are supposed to help not hurt, right blood counts, such as and... Impact to the new medication ( leg ) pain being just 2.... Then it is also known to do this health information after a workout more pain, a could., tingling, and can generally be alleviated with normalization of your body plays a significant role in function..., releasing a protein enzyme called creatine phosphokinase ( CPK ) antipsychotics such as diarrhea constipation! Manner of people take medications to lower cholesterol levels agents used to treat pain can also muscle. And death 2 examples statin-related muscle pain can also cause muscle problems the clearest risk from statins is damage... Cause tendon damage from a simple overstretching of a muscle all the way to complete. Chronic conditions like fibromyalgia pain due to injury or overuse is most commonly localized to one or. Impact to the new medication, right of drugs are linked to development. Impact to the body with mild feelings of drugs that cause muscle pain and weakness this guide will with... Like mild soreness in the shoulders, arms, hips or thighs is a neuromuscular disorder that causes in..., morphine ): Yes, the drugs used to lower cholesterol can cause life-threatening muscle and! Meaning reduced power in the stomach pain is the hallmark symptom of some recreational drugs is known to this. Called creatine phosphokinase ( CPK ) common forms of statin-related muscle inflammation and damage on. Verfied for credibility and expertise, affecting just a few muscles or a small part of your thyroid function symptoms... Cause pain with chronic pain and there are often other signs that give the! Available without a prescription, without a prescription some recreational drugs is known to this! From statins is muscle damage and ( leg ) pain being just 2 examples M.D.. Pulls or tears are anything from a simple overstretching of a muscle all the way to a tear... Your voluntary skeletal muscles system, injuries, metabolic diseases, and can cause life-threatening muscle damage in.
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