terahertz therapy side effects

Intense THz pulses cause H2AX phosphorylation and activate DNA damage response in human skin tissue. To Get More up to date details about this amazing health blower go here. Li ML. Biomedical optics applications of advanced lasers and nonlinear optics. 6. , The progress and perspectives of terahertz technology for diagnosis of neoplasms: a review, J. Opt. CAS PubMed Central Studies from other groups indicated that terahertz waves have no obvious effect on the structures and functions of DNA. Nov. 30, 2018 New accelerator-based technology aims to reduce the side effects of cancer radiation therapy by shrinking its duration from minutes to under a second. Side effects tend to start a week or 2 after the radiotherapy begins. [43] revealed that C57BL/6J mouse skin tissue interleukin-1beta (IL-1), interleukin-6 (IL-6) and tumor necrosis factor- (TNF-) was significantly increased after exposure to 0.22 THz with an average power density of 50mW/cm2 for 5min. If those side effects are caught early, they may be less serious, easier to treat, and less likely to lead to discontinuation of your cancer therapy. Generally, it is believed that THz waves can strongly affect organisms due to their biophysical properties and unique responses in organisms [31, 32]. Measurement of tissue optical properties in a wide spectral range: a review [Invited]. Chin J Lab Med. The composition and topology of DNA molecules are very sensitive to the movement of hydrogen bonds, which strongly depended on the double-stranded base pair. Chen T, Cai ZH, Hu FR, Yin XH, Xu CP. 34(10), 810824 (2016).TRBIDM10.1016/j.tibtech.2016.04.008 As a result of life it affects us in different ways. Biological effects of in vitro THz radiation exposure in human foetal fibroblasts. Red light therapy uses the therapeutic application of light energy primarily to aid in the healing of skin and muscular conditions, such as scarring and tendonitis. iTeraCare Terahertz waves are non-ionizing and non-invasive. Safonova TN, Fedorov AA, Surnina ZV, Sikach EI, Ozheredov IA. Song GA. These researchers found that terahertz waves promoted the differentiation of mouse pluripotent stem cells after 12h of radiation by upregulating the expression of peroxisome proliferator-activated receptor gamma, adiponectin, glucose transporter 4 and human adipocyte fatty acids. In past decades, terahertz technology has been widely used in various fields, such as aerospace, communications, security, and biomedicine. In 2005, Japan listed Terahertz Technology as the first of the Ten Key Strategic Objectives of the National Pillars, and the nation is aggressively engaged in research and development. Side effects and risks Gua sha causes tiny blood vessels near the surface of the skin called capillaries to burst. Anticancer drugs are pivotal to cancer treatment, but their toxicity may not always be limited to cancer cells, resulting in harmful side-effects. Dogs are amazing friends and loves the iTeracare device! Fu WL, Huang Q. However, because our cells have become impenetrable the food, supplements and therapies we apply only deal with the remaining energy and we are unable to get our cells full. Within 5yrs of being with us, James has been over free and managed to put his life in dangerous situations: he once tumbled off a cliff. Consistent with that on proteins, the effects of terahertz waves on DNA and RNA were determined by radiation sources, radiation frequency, intensity and duration. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. All genetic information is stored in DNA by the order of paired bases. J Mol Struct. When its new and full, the torchlight is bright and clear, as we use it, the more we use it, the quicker the light diminishes. 2020;42(23):22829. J Cap Nor Univ. On the left side, there are microwaves and longer radio waves. The resolution of the detection system is inversely related to the wavelength of the emitted wave. For example, different amino acids have different peak positions in the terahertz spectra [14,15,16,17,18,19,20]. However, it could excite the rotational energy level of proteins to alter the spatial conformation and might influence the interactions between proteins. Nucleic acids can be divided into two groups: DNA, which is mainly located in the nucleus, and RNA, which is always distributed in the cytoplasm. My head had stopped bobbing and I was speaking normally. Terahertz waves are sensitive to the alteration of DNA structures mainly through a collective vibrational mode, which is determined by molecular configuration and spatial conformation. FOIA [53] radiated C57BL/6J mouse retinal tissue at the average power density of 80mW/cm2. The picosecond optical pulse of a terahertz wave results in a wide electromagnetic frequency band ranging from GHz to tens of THz. The terahertz range of electromagnetic radiation has large potential in the field of hidden objects detection because it is not harmful to humans [1, 2]. Chen et al. [49] also revealed that human skin fibroblasts and human hamster hybrid cell lines were not sensitive to 0.106 THz terahertz waves, and no DNA strand break was detected under power densities between 0mW/cm2 and 2mW/cm2 for 2, 8 and 24h. At the RNA level, a specific terahertz wave could affect gene expression. Infrared bands include far-infrared, Mid-infrared and near-infrared. with the permission of MDPI. Unauthorized use of these marks is strictly prohibited. We often ask what causes cancer or what causes Irritable Bowel etc there are so many contributing factors & combinations its impossible to answer. [55], who used a gas-phase terahertz laser to radiate human skin fibroblasts for 80min at 2.52 THz in a temperature-controlled chamber. Before Phys Lett A. Inflammation, pain, Rhinitis, Pharyngitis, gastritis, ayrecological, inflammation, prostatitis, 10. Google Scholar. Terahertz irradiation-induced motility enhancement and intracellular calcium elevation in human sperm in vitro. 2023 BioMed Central Ltd unless otherwise stated. Apricity Health has created the Apricity CARE program, which includes a smart phone app called ApricityCare for monitoring and Article April 05, 2023 Penn Medicine, Virtua Health open proton therapy cancer treatment center in South Jersey The radiation is used to treat a wide range of cancers and is associated with fewer side effects In 2009 I was injured by a flu shot. Bookshelf 2009;29(11):28858. When we were conceived we took onboard family characteristics and predispositions that have influenced us daily. WebLower blood viscosity: Terahertz water has the ability to thin the blood, which can help to lower blood pressure and improve circulation. Terahertz waves could be strongly absorbed by water. https://doi.org/10.1364/BOE.8.000273. WebThere are no side effects, but there are a few limitations. Terms and Conditions, The nucleoside absorption peak mainly originates from hydrogen bonds, which link pentose and pentose, pentose and base, base and base [21]. Serdyukov. An official website of the United States government. Detection of colon cancer by terahertz techniques. Moreover, terahertz could not alter the conformation of adsorbed proteins, which might be attributed to the adaptive capacity to terahertz wave exposure [46]. In 2004, the US government rated Terahertz Technology as one of the Ten Technologies that will change the world of the future. Therefore, terahertz waves belong to the far-infrared spectrum in the field of radiophysics and are also defined as submillimeters lying between millimeter waves and infrared light in the field of optics, as shown in Fig. If those side effects are caught early, they may be less serious, easier to treat, and less likely to lead to discontinuation of your cancer therapy. government site. Titova LV, Ayesheshim AK, Golubov A, Fogen D, Rodriguez-Juarez R, Hegmann FA, et al. This review helps the biomedical optics community to summarize up-to-date knowledge in the area of cell exposure to THz radiation, and paves the ways for the development of THz safety standards and THz therapeutic applications. Detoxification. [58] used a wide-band terahertz source to radiate three different types of cells, epithelial cells, human corneal epithelial cells and human M lymphocytes, under an 800nm pulse with a repetition rate of 1kHz, an average power of 1mW and a peak power of up to 2mW. Thermal effects of THz exposure are also applicable in cancer treatment, but they are less studied. Careers. The data bandwidth exceeds wireless protocols e.g. literally! (a)Microscopy of the unaltered neural network. I had had some neurological issues for at least 6 years. There are few limits as to how you can use the iTeraCare terahertz blower device on problem areas. Shenyang: Northeastern Univ; 2009. The benefits and features of the Terahertz stone are endless. But his scars are huge, physically and psychically. 2003.http://www.cnki.com.cn/Article/CJFDTOTAL-SCEL200304023.htm. 1) Molecular vibrational model. (a)Total number of over- and underexpressed messenger RNAs (mRNA) at the 1.4, 2.52, and 3.11THz exposures. A unique terahertz spectral fingerprint might be defined for each biomacromolecule [4]. Therefore, the THz time-domain spectroscopy technique is a sensitive tool to analyze the structural alteration of carbohydrate molecules. The day John came my brain was very tired, I was having trouble speaking, my head was bobbing and my arms and hands were tremoring very badly. In 2005, China listed Terahertz Technology as one of the Ten Key Strategic Goals of Nation. In 2014, China held the Xiangshan Science and Technology Conference to formulate a plan for accelerating research of the application of Terahertz Technology in biomedicine. Briefly, terahertz waves altered the space conformation of biomacromolecules by exciting rotational energy levels, which in turn influenced the effects on biomacromolecules and finally resulted in structural and functional changes in organisms. Courtesy of the authors. Tianjin: Tianjin Univ; 2012. [41] showed that after continuous terahertz radiation at (0.120.18) THz with an average power density of 3.2mW/cm2 for 5min, the space conformation of membrane proteins was changed, several apoptotic proteins were released from mitochondria to cytoplasm, and proteolytic enzymes were also released from lysosomes in the glial cell line C6. CAS Better absorption. Therefore, terahertz waves have the potential to be developed as a much more effective tool for analyzing the composition, structure and function of biomacromolecules. Get the details about iTeracare Magic Wand here. 2010;37(2):1218. IR. 2012;26(6):47183. cardboard, ceramics, clothing, masonry, paper, plastic, and wood). https://doi.org/10.3967/bes2019.094. (b)Results of the fluorescence microscopy of the actin filaments in control sample (top) and that exposed to THz waves with the irradiance of. I thought he was dead. Studying the non-thermal effects of terahertz radiation on E. coli/pKatG-GFP biosensor cells. Attached is a before and after a 30 min session only the second time I used it. https://doi.org/10.3964/j.issn.1000-0593(2009)11-2885-04. https://doi.org/10.1002/bem.20466. Scanning electron microscopy of the PheoChromocytoma (PC12) cells after 10-min-long THz exposure. [27] detected the absorption spectra of D-()-ribose, D-glucose, -lactose monohydrate and -lactose. Would you like email updates of new search results? (a)Schematic of the experimental setup. 2021;137(3):58-67. doi: 10.17116/oftalma202113703158. (b)Dependence of the permeation transition on the THz-wave frequency. 2020;42(23):225966. Accelerate metabolism. I started having head shakes like I had Parkinsons. J Biomed Opt. Similar results were reported by Wilmink et al. See more, Clickhere for iTeraCare Device Review Videos, Demos and Personal Life Stories. https://doi.org/10.3760/cma.j.issn.1009-9158.2015.01.001. Zhou J, Liu SG. [Experimental investigation of the safety of terahertz radiation in corneal hydration assessment]. CAS Effects of 100 GHz radiation on alkaline phosphatase activity and antigen-antibody interaction. Typical dimensions of, Double-Debye models of the complex dielectric permittivity for water and epidermis, Simulated time-dependent evolution of the, Simulated time-dependent evolution of the temperature distributions in cornea heated by the THz, Numerical data on transition to a superpermeation phase of confined water across a, Important technical factors for the experimental studies on THz irradiation. The summarized data demonstrate the current stage of the research activity and knowledge about the THz exposure on living objects. Moreover, the terahertz wave and vibration of the protein structural domain fall on the same time scale, so they can reflect the transient characteristics of macromolecules [7]. It can penetrate many materials (i.e. With zero success. Research on the terahertz spectrum of lipids is deficient. 1) Temperature. In this work, we propose a physical method, terahertz wave modulation, to promote the dissociation of high-affinity antipsychotics and thus diminish the side effects. Mod Appl Phys. Google Scholar. National Library of Medicine Google Scholar. He came home. The interaction between terahertz and biomacromolecules is very important. Bogomazova et al. See this image and copyright information in PMC. WebHere are some common side effects to using terahertz devices from iTeraCare that you might experience during use or shortly after: Feeling hot/cold: When a person feels hot AND THIS IS WHERE THE MAGIC WAND COMES IN! For example, Braverman and colleagues 25 demonstrated this indirect effect by creating matching skin lesions on the left and right dorsum of a rabbit, treating 1 side with infrared light. Tech Auto Appl. 8600 Rockville Pike THz waves with the frequency of 4.0 THz radiate this dish with a liquid sample from the bottom side. Therefore, further investigations should be conducted in the future. WebA thorough explanation of the effects and meaning of Terahertz. https://doi.org/10.1002/bem.20343. Terahertz radiation accelerated chondrocyte differentiation of MSCs. I have not walked with a walker since that first night. Feels hopeless huh!!! Xie MZ, Jiang LY, Che TJ, He JC. Optical Quartz amplifies the energy generated by the device, creating a more powerful result. 2012;7(9):e46397. J Third Mil Med Univ. Permeability changes induced by 130 GHz pulsed radiation on cationic liposomes loaded with carbonic anhydrase. Inspiration for terahertz radiation induced biological effects on cells. Nov. 30, 2018 New accelerator-based technology aims to reduce the side effects of cancer radiation therapy by shrinking its duration from minutes to under a Research in development of viable sources of THz radiations, detectors and modulators have expedited possibilities of use of Terahertz in wireless communications. It offers greater bandwidth than microwave frequencies. The data bandwidth exceeds wireless protocols e.g. 802.11b. Detoxification: Terahertz water may help The functional role and development prospect of nucleic acids. Gene expression profiles of the human epidermal keratinocytes exposed to the THz radiation at different frequencies. Zhao JW, He MX, Dong LJ, Li SX, Liu LY, Bu SC, et al. WebA: Terahertz waves do not damage body cells and tissues even with repeated exposure. Wahaia F, Valusis G, Bernardo LM, Almeida A, Moreira JA, Lopes PC, et al. Exposure Effects of Terahertz Waves on Primary Neurons and Neuron-like Cells Under Nonthermal Conditions. Nikitkina AI, Bikmulina PY, Gafarova ER, Kosheleva NV, Efremov YM, Bezrukov EA, Butnaru DV, Dolganova IN, Chernomyrdin NV, Cherkasova OP, Gavdush AA, Timashev PS. Society of Photo-Optical Instrumentation Engineers. Beijing Institute of Radiation Medicine, Haidian District, 27 Taiping Road, Beijing, 100850, China, You can also search for this author in Progress in lipid omics. When a protein is excited by terahertz waves, its vibrational properties are altered, resulting in corresponding changes in the absorption spectrum [5]. The present work proposes the THz generation by the interaction of two hat-top laser beams with a host medium of argon gas containing Zeni O, Gallerano GP, Perrotta A, Roman M, Sannino A, Sarti M, et al. Sci Rep. 2015;5(1):7749. https://doi.org/10.1038/srep07749. Now lets think of a battery. , Biomedical applications of terahertz spectroscopy and imaging, Trends Biotechnol. Intense THz pulses down-regulate genes associated with skin cancer and psoriasis: a new therapeutic avenue? J Third Mil Med Univ. I was shocked, and elated. 2015;793:15060. WebResults: The reviewed results demonstrate the possibilities of THz spectroscopy and imaging, both pulsed and continuous, for diagnosis of skin melanoma and non In this paper, we reviewed terahertz waves and their biomedical research advantages, applications of terahertz waves on biomacromolecules and the effects of terahertz waves on biomacromolecules. (a)Water permeation is strongly and nonlinearly modulated by a 1.39-THz radiation (red squares), but weakly and linearly affected by temperature (blue squares). 2011;1006(1):7782. Article (b)Decrease in the amplitude of a resonant THz-wave absorption peak during the demethylation process. Terahertz molecular resonance of cancer DNA. Chen CH, Ma QL, Tao JW, Lu YH, Lin M, Gao P, et al. Hed bark his fear at any noise..he s still(after 5 yrs) reactive to high pitched soundsand can hear for miles..I had rescued before him a wee dachshund female..shed been chained up for 2yrs alone in a barnfull of ticks and fleas and her own shit..SHE was fearless, joyfull,full of life and just wanted to explore further than her schnozz..the most beautiful gentle soul..she, Cajou, taught her big brother James a lot. Is the new terahertz blower from iTeraCare too good to be true. Meditating with it can help improve sleep, promote metabolism, relieve stress and anxiety, reduce pain and treat inflammation. Lipids can be classified into three groups: fats, lipids (phospholipids) and sterols (cholesterol, sex hormones and vitamin D). Studies have reported that terahertz wave radiation alters the activity and expression of proteins, which is closely associated with radiation intensity [38]. Mutat Res Genet Toxicol Environ Mutagen. https://doi.org/10.16016/j.1000-5404.202008145. https://doi.org/10.3969/j.issn.1004-9398.2004.04.006. Biomed Opt Express. I see many questions and comments about specific ailments, diseases, conditions, pain etc it has inspired to give a simple explanation that I hope will be enlightening and encouraging to all magic wand users. De Amicis A, Sanctis SD, Cristofaro SD, Franchini V, Lista F, Regalbuto E, et al. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. (a) Refractive index n and absorption, Dimensions of the tissue structural elements at the THz-wavelength scale. It has generally been considered to be safe for use in tissues, though some recent studies have found that it may have some direct effect on DNA, though it has Thus, a well-balanced diet during radiation therapy helps to counteract the adverse effects of cancer and side effects of cancer treatment. Reprinted from Ref. Zhang et al. J Third Mil Med Univ. https://doi.org/10.16016/j.1000-5404.202008140. https://doi.org/10.3724/SP.J.1206.2009.00562. 2006;8:40915. 2013;58(2):37391. Part of 2008;28(10):223742. [42] discovered that green fluorescent protein expression was induced in Escherichia coli after exposure for 15min under constant terahertz radiation at 1.4W/cm2. Sci Rep. 2016;6(1):37103. https://doi.org/10.1038/srep37103. Terahertz time-domain spectroscopy study of structurally similar monosaccharide and disaccharide molecules. If we cut the battery in half, it would not recharge to full again and so our cells are replicating to the level they have gotten down too. An increasing interest in the area of biological effects at exposure of tissues and cells to the terahertz (THz) radiation is driven by a rapid progress in THz biophotonics, observed during the past decades. These researchers found that lactose monohydrate had three absorption peaks at 0.53, 1.19 and 1.38 THz, while D-glucose only had one absorption peak at 1.44 THz, suggesting that lactose monohydrate and D-glucose presented different terahertz fingerprint absorption characteristics. 6(2), 020201 (2020).10.18287/JBPE20.06.020201 Due to different individual physical body structure, some may experience pain on certain areas. WebFollowing are the benefits or advantages of Terahertz (THz): It offers greater bandwidth than microwave frequencies. Although research on the relationship between terahertz waves and biological macromolecules is still in its infancy, we believe that major breakthroughs will be realized in the near future with the efforts of professional scholars and the application of advanced terahertz instruments. The absorption of different sugars in the measured band was significantly different. Bioelectromagnetics. -. Lets look at how and why this happens. Photonics Eng. The THz range of the electromagnetic spectrum. 1990;87(7):28102. J Electron Meas Instrum. Amino acid detection based on terahertz spectroscopy. Other times I would know I was on a flat surface but would look like I was climbing stairs. 2004;27(7):53440. Direct Entry into Cells. The condition I have is called FND or functional neurological disorder. https://doi.org/10.1016/j.mrgentox.2015.06.003. More testimonials on our youTube channel. I kept saying I just dont feel right. All authors read and approved the final manuscript. Lu et al. However, to our knowledge, there are still no publications on the application of terahertz spectroscopy for RNA detection. WebAbstract Significance: An increasing interest in the area of biological effects at exposure of tissues and cells to the terahertz (THz) radiation is driven by a rapid progress in THz Ma et al. WebFor stronger THz radiation generation, laser and plasma interaction has been investigated in detail focusing on laser pulse shape effects, collisional effects and density ripples contribution in the mechanisms such as beating and photo-mixing. Polysaccharides, carbohydrates with complex molecular structures, are formed by condensation and dehydration of many monosaccharide molecules. The primary object for applying terahertz technology in the biomedical field is to illuminate biological phenomena by revealing the basic rules of interactions between macromolecules and macromolecules, as well as cells and cells. The functions and activities of proteins are largely dependent on specific structures and space conformations. 2007;56(2):7815.

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